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1. A Green, Asymmetric Total Synthesis of the Antiviral Natural Product Sattabacin

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The sattabacins and sattazolins are fascinating natural products isolated from soil bacteria by Italian researchers. These natural products were shown to exhibit potent antiviral activity against various viruses including herpes simplex virus (HSV) type 1 and type 2 in the µg/mL range. Sixty million Americans are infected with HSV-2, an incurable viral infection, and numerous studies have shown that HSV-1 infection leads to a higher risk of developing...
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